5. New Orleans Saints vs. San Fransisco 49ers
Monday Night- 8:00pm
Candlestick Park- San Fransisco, CA
Candlestick Park- San Fransisco, CA
- Where will be the focus of the Saints offense: The run game or the passing game?
- Is a home game the medicine that'll get the 49ers back on the right track?
- Will the NFC West favorite 49ers really start their season 0-2?
Sunday Afternoon- 1:00pm
Paul Brown Stadium- Cincinnati, OH
Paul Brown Stadium- Cincinnati, OH
- Can Carson Palmer stay consistent and play the whole game as he did in the second half of last game?
- Will Chad Ochocinco and Terrell Owens play level headed against a tough defense?
- Is this the game where Ray Rice breaks out in 2010?
3. Pittsburgh Steelers vs. Tennessee Titans
Sunday Afternoon- 1:00pm
LP Field- Nashville, TN
- How will the loss of Casey Hampton up the middle effect the Steelers ability to stop Chris Johnson?
- What will the Steelers do to minimize the effect of Vince Young on the offense?
- How will Dennis Dixon look after a respectable outing in Week One at home against the Falcons?
2. New England Patriots vs. New York Jets
Sunday Afternoon- 4:15pm
New Meadowlands Stadium- East Rutherford, NJ
- Who will win the battle: The explosive Patriots offense or the dominating Jets defense?
- Can slightly banged up (hamstring) Darrelle Revis shut down Randy Moss?
- Will the Jets offense finally get going?
1. New York Giants vs. Indianapolis Colts
Sunday Night- 8:20pm
Lucas Oil Stadium- Indianapolis, IN
- How will the Colts shake off their tough first week loss to the Texans?
- Will the Colts be able to stop the Giants run game with the loss of Bob Sanders?
- How many times will we hear it mentioned that the Manning's are brothers?
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